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Candida, Sacchromyces, and Your Body’s Many Fungal Strains | BIOHM Health

Candida, Sacchromyces, and Your Body’s Many Fungal Strains | BIOHM Health

In part 2 of our three part series, we’re discussing the role of fungus in the microbiomes of our bodies. Dr. Ghannoum is back in the studio talking about how fungi are more closely related to us than we might imagine. He also sheds light on his favorite microorganism, Candida.

Transcript:
Andrea Wien:
I’m functional nutritionist, Andrea Wien and this is the Microbiome Report powered by BIOHM Health. In the first episode of this three part series, we took a look at the microbiome to understand what it is, where it lives and why we should care. In this episode, I’m joined again in the studio by Dr. Mahmoud Ghannoum, the director of the Center for Medical Mycology at Case Western Reserve University and University Hospitals, Cleveland Medical Center. We dissect the wide world of fungus, and I learned that our fungi guy friends are more similar to us humans than they are to plants. By the end of this episode, you’ll have a new appreciation for all things, fungus, and you may even be able to give the most famous fungi of the moment. That’d be candida, a bit of a break. So happy to have Dr. Ghannoum back in the studio today, talking to us about his favorite topic, fungus. So thank you for being here.

Dr. Mahmoud Ghannoum:
Thank you very much, it’s my pleasure always.

Andrea Wien:
So let’s talk about what is fungi, because I think a lot of people think they know what bacteria is, makes us sick, helps our microbiome. Not as many people know exactly what is fungus, is it the mushrooms that we eat? Is it something different?

Dr. Mahmoud Ghannoum:
Well, definitely mushrooms is one of organisms which are fungus. So yes, everybody should know fungus because we all eat mushrooms, even so some people may not like it, but they know it. Now fungi for very long time, people used to think it is like a plant most probably because of the mushroom. But in fact, it is different from plants. You have, for example, bacteria is one group and then fungi is another, both of them are microorganisms or microbes, but they differ. Okay. In fact, fungi is very close to us. Like as we have similar structure of cells like fungus, and that’s why a lot of the time when we’re trying to see how we can control fungus using, let’s say antifungal agent or a drug that kill fungus, it’s difficult because they are like us. So you can think about fungi as more close to us than bacteria.

Andrea Wien:
How so? That doesn’t even make sense to me.

Dr. Mahmoud Ghannoum:
Well, because listen, I mean, when you look at the structure of the fungal cell, it has a nucleus. Where as bacteria does not have nucleus. We as a human, we have a nucleus. So that’s why we are closer to it.

Andrea Wien:
Okay. Okay. What is the overall impact on our health and wellness in terms of fungi? How does it affect those areas?

Dr. Mahmoud Ghannoum:
So let me tell you first like about fungi again, and then we’ll come into the health. Fungi, it’s not only the mushroom, for example, fungi, we have good fungus and we have some fungus, which is cause problems. Good fungus, the best example is the one like penicillium, which is the fungus that produce penicillin the antibiotic, which really changed the way we manage infections. So this is a good fungus. You have another good fungus, for example, for making bread or brewing the beer we drink without fungus will be in a bit of a [crosstalk 00:03:12].

Andrea Wien:
Okay. Now I’m seeing how we’re connected the beer and the… I get it all now. Okay.

Dr. Mahmoud Ghannoum:
So, and that’s why we have a fungus called Saccharomyces, which makes beer, we use it to ferment bread as well as beer. So that’s the good side of the fungus, but there are some other fungus which could cause problems. Now, as we mentioned before, in the previous recording, some of these organisms, the fungus, the bad one in general, they don’t cause a lot of trouble. The only time they start to cause these become pathogenic or virulent, the only time they cause problem is when our body change, I call fungus always the organism of the immunocompromised. It cause infection. If your immunity is down or if you are using some drugs, which can to encourage it, to grow and overgrow. So this is the two types of fungus, which we can think about.

Andrea Wien:
So when someone gets something like Tinea Versicolor on their skin, which is a fungus that causes your skin to look splotchy, almost like vitiligo or someone has athlete’s foot. And that’s a fungus that’s causing that. You would say that there’s a immunocompromised state, that that person is in. And that’s why that fungus is able to take over and something like the skin.

Read More: https://www.biohmhealth.com/blogs/pod-cast/episode-2-candida-sacchromyces-and-your-body-s-many-fungal-strains

This episode of The Microbiome Report is powered by BIOHM Health, a wellness company designed to help you optimize your gut.